In rare cases PMP could spread outside the peritoneum. This happens for different reasons including:
1- A congenital defect that causes the communication between pleural and peritoneal space.
2- Tumor progression
3- Surgical error: where the surgeon creates a hole in the diaphragm during the removal of tumor.
In a select group of patients with pleural spread of the disease, the treatment involves parietal and visceral pleurectomy followed by hyperthermic intrapleural chemotherapy.
Your PMP specialist would be able to tell you if you are a candidate for this treatment.
The following articles discuss this condition:
Zappa, L. Savady, Renaldo; Humphries, Gary N.; Sugarbaker, Paul H. Interstitial pneumonitis following intrapleural chemotherapy. World Journal of Surgical Oncology February 12, 2009
Pestieau SR, Esquivel J, Sugarbaker PH. Pleural extension of mucinous tumor in patients with pseudomyxoma peritonei syndrome. Ann Surg Oncol 2000;7:199–203.
Pestieau SR, Wolk R, Sugarbaker PH. Congenital pleuroperitoneal communication in a patient with pseudomyxoma peritonei. J Surg Oncol 2000;73:174–8.
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1 comment:
Hi, interesting blog. I had cytoreductive surgery and HIPEC last year and have found a great support group on Facebook.
The registered charity Pseudomyxoma Survivor is a great resources, it would be good if you could at it to your list!
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